' 
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 46 Reviews
8.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
Most Useful Reviews
9
Thins blood effectively
Inositol is a vitamin-like substance, a soluble alcohol that normalises the digestive tract, lowers blood pressure, and blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I highly recommend it.
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9.5
Prevents blood clots
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
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9.5
Good combination for health
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 46 Reviews
8.9
9.5
Stabilises panic attacks
I'm a 44-year-old woman experiencing severe panic attacks due to declining ovarian function. This inositol supplement has surprisingly stabilised my condition day by day. I feel saved, and my hair loss has since stopped. I intend to continue using this supplement.
9.5
Good combination for health
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
9.5
Balances blood glucose levels
I use Inositol for an elderly individual with diabetes and it has significantly improved his health over the past few months. It effectively stabilises blood sugar levels and enhances metabolism from the first month. Importantly, it lowers the risk of diabetes-related complications and supports nervous system health, making it a valuable addition to his treatment plan.
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9.5
Reduces risk of atherosclerosis
The quality and ingredients of inositol are commendable. Known as the "vitamin of youth," it improves fat metabolism, lowers blood cholesterol, and reduces atherosclerosis and obesity risks. It also enhances blood fluidity, preventing the formation of blood clots and stabilising blood sugar to help control appetite.
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9.5
Alleviates panic attacks
This supplement is beneficial for the nervous system, aiding in alleviating panic attacks while assisting in liver and hormonal restoration. It enhances concentration, memory, and blood vessel health by preventing blood clot formation and reducing the risks of atherosclerosis and obesity. Consistently high quality from iHerb.
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