Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 46 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
Most Useful Reviews
8
Thins blood effectively
214 people found this helpful
Inositol is a vitamin-like substance, a soluble alcohol that normalises the digestive tract, lowers blood pressure, and blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I highly recommend it.
Read More
9
Prevents blood clots
186 people found this helpful
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
Read More
9
Good combination for health
127 people found this helpful
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 46 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
8
Thins blood effectively
214 people found this helpful
Inositol is a vitamin-like substance, a soluble alcohol that normalises the digestive tract, lowers blood pressure, and blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I highly recommend it.
Read More
9
Prevents blood clots
186 people found this helpful
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
Read More
9
Good combination for health
127 people found this helpful
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
9
Prevents blood clots
14 people found this helpful
Inositol is known as the “vitamin of youth” because it aids in fat metabolism, lowers cholesterol levels in the blood, and thereby reduces the risk of developing atherosclerosis and obesity. Vitamin B8 also enhances blood flow, prevents blood clot formation, and helps maintain the elasticity of artery walls.
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9
Helpful for fertility
9 people found this helpful
Life-changing! After a few months on inositol, I noticed a difference with my PCOS symptoms—weight loss and blood sugar regulation. After being infertile for 2.5 years, I fell pregnant shortly after starting this. It truly assists women with fertility challenges, more so than metformin with its side effects.
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Frequently Asked Questions
9
Weight loss aid
3 people found this helpful
I'm shocked after just twenty days! I lost 5.5 kilograms, finally reaching my goal weight after years of struggle. My cholesterol was high, but I committed to exercising and using inositol along with healthy eating and intermittent fasting. I feel proud as inositol helped reduce my appetite, especially for those with stable weight and insulin resistance. This treatment has truly changed my life!
9
Normalised blood tests
5 people found this helpful
I had a hematopoietic stem cell transplant 12 years ago, but my liver is still affected. I developed fatty liver and sought a supplement to improve liver function. Upon taking inositol with each meal for under a month, my blood test results returned to normal. It worked immediately, and I'm very pleased!
9
Normalises menstrual cycle
5 people found this helpful
Inositol is essential for lowering blood sugar and insulin levels. After six months, I observed positive hormonal changes in my PCOS status, including decreased androgen levels and normalised LH/FSH ratios. This helped restore my ovulatory menstrual cycle. I recommend it for anyone facing similar issues!
7.5
Reduces swelling effectively
11 people found this helpful
I noticed my shoulders were quite stiff and cold. Since taking this supplement, I’ve experienced improved blood flow and reduced swelling, eliminating the need for water pills. It has alleviated fatigue, allowing me to feel clear-headed again. One tablet in the morning has made a significant difference.
9
Prevents blood clots
186 people found this helpful
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
9
Good combination for health
127 people found this helpful
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
9
Enhances egg quality
4 people found this helpful
Inositol was recommended by my gynaecologist to combat PCOS and improve oocyte quality. It also normalises digestion, lowers blood pressure, and decreases blood sugar levels. This vitamin is essential for athletes as it activates lipid metabolism. Furthermore, inositol maintains the elasticity of blood vessel walls, thins the blood, and prevents blood clots.
9
Reduces risk of atherosclerosis
1 people found this helpful
The quality and ingredients of inositol are commendable. Known as the "vitamin of youth," it improves fat metabolism, lowers blood cholesterol, and reduces atherosclerosis and obesity risks. It also enhances blood fluidity, preventing the formation of blood clots and stabilising blood sugar to help control appetite.
7.5
Beneficial for diabetes
69 people found this helpful
Inositol is essential for managing PCOS and diabetes. I've switched to ordering it from iHerb as it helps lower blood triglycerides, enhances insulin sensitivity, reduces blood pressure, and promotes ovulation in women. This supplement has become a staple in my health regimen, and I highly recommend it.
6
Enhances ovarian function
26 people found this helpful
Inositol has proven beneficial for polycystic ovary syndrome, lowering triglycerides and testosterone levels while improving ovarian function, particularly in overweight women. My gynecologist recommended it for enhancing egg quality, and I take four capsules a day, as it's not readily available locally. I am hopeful for positive outcomes.
9
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
References
- Al-Horani RA, Abdelfadiel EI, Afosah DK, Morla S, Sistla JC, et al. A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding. J Thromb Haemost. 2019;17:2110. doi:10.1111/jth.14606
